Head to head
Compare products
Pick up to four tracked products. Everything below comes from the most recent snapshot, so the price and model rows are as fresh as the last crawl.
ESM3Chai
| Attribute | ESM3 EvolutionaryScale | Chai Chai Discovery |
|---|---|---|
| Segment | Science & Bio | Science & Bio |
| Version | ESM3 | Chai-1 |
| Entry cost | ESM3-open is free on GitHub. Other ESM3 model sizes are available via the Biohub Platform API (pricing not listed). | Pricing is not publicly listed (enterprise/licensing) |
| Pricing tiers | ESM3-open free | — |
| Model stack | ESM Cambrian · ESM3 · ESM3 (98B) · ESM3 (Large) · ESM3 (Medium) · ESM3 (Small) · ESM3-open | Chai · Chai biological models · Chai-1 · Chai-2 |
| Context window | — | — |
| Public API | ||
| Routes models | ||
| Changes / 30d | 3 | 8 |
| Origin | United States | United States |
| Capabilities | Protein generation, Sequence-structure-function, Open weights, Forge API, sequence modeling, structure generation, function design, protein generation | De novo binders, Complex prediction, Antibody design, Web tool, drug discovery, molecule design, antibody discovery, molecular design |