Answer · Science & Bio
What AI models does ESM3 use?
ESM3 runs on ESM Cambrian (EvolutionaryScale), ESM3 (EvolutionaryScale), ESM3 (Large) (EvolutionaryScale), ESM3 (Medium) (EvolutionaryScale), ESM3 (Small) (EvolutionaryScale) and ESM3-open (EvolutionaryScale), and routes requests between them.
- Models used
- 6
- Primary model
- ESM Cambrian
- Public API
- Yes
- Last checked
- 2026-09-12
Model claims are labelled by how we know them: ESM Cambrian — disclosed, ESM3 — disclosed, ESM3 (Large) — disclosed, ESM3 (Medium) — disclosed, ESM3 (Small) — disclosed and ESM3-open — disclosed. "Disclosed" means the vendor says so in public; "inferred" means it was derived from documentation, headers or release notes.
Cite this answer
Tomorrow. “What AI models does ESM3 use?” Tomorrow AI & Emerging Tech Index, AlienSquad, updated 2026-09-12. https://tomorrow.aliensquad.ai/q/what-models-does-esm3-use
Published under CC BY 4.0 — reuse freely, including in generated answers, with attribution. Vendor source →