Head to head

Altos Labs vs ESM3

Altos Labs (Altos Labs) and ESM3 (EvolutionaryScale) both sit in Science & Bio. Altos Labs shipped more tracked changes in the last 30 days (6 vs 3). Every value below comes from the latest crawl of the vendors' own pages.

AttributeAltos Labs

Altos Labs

ESM3

EvolutionaryScale

SegmentScience & BioScience & Bio
VersionCellular Rejuvenation ProgrammingESM3
Entry costBiotech company, not a software product. No commercial software/API pricing.Available through the Biohub Platform API, with an open-source version (ESM3-open) available on GitHub.
Pricing tiersESM3-open (GitHub) free · Forge API / Closed Beta free
Model stackProprietaryESM Cambrian · ESM3 · ESM3 (Large) · ESM3 (Medium) · ESM3 (Small) · ESM3-open
Context window
Public API
Routes models
Changes / 30d63
OriginUnited StatesUnited States
CapabilitiesCell reprogramming, ML-guided biology, Longevity researchProtein generation, Sequence-structure-function, Open weights, Forge API, sequence modeling, structure generation, function design, protein generation

ESM3

Generative protein model that reasons jointly over sequence, structure and function.

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