Head to head

FutureHouse vs ESM3

FutureHouse (FutureHouse) and ESM3 (EvolutionaryScale) both sit in Science & Bio. FutureHouse shipped more tracked changes in the last 30 days (4 vs 3). Every value below comes from the latest crawl of the vendors' own pages.

AttributeFutureHouse

FutureHouse

ESM3

EvolutionaryScale

SegmentScience & BioScience & Bio
VersionRobinESM3
Entry costFree / Open research (Non-profit organization)ESM3-open is free on GitHub. Other ESM3 model sizes are available via the Biohub Platform API (pricing not listed).
Pricing tiersNon-profit / Open research freeESM3-open free
Model stackMultiple · Robin · Robin (multi-agent system)ESM Cambrian · ESM3 · ESM3 (98B) · ESM3 (Large) · ESM3 (Medium) · ESM3 (Small) · ESM3-open
Context window——
Public API
Routes models
Changes / 30d43
OriginUnited StatesUnited States
CapabilitiesLiterature agents, Open source, Robin/Falcon agents, Hypothesis generation, AI agents, scientific discovery, biology research, AI agents for biologyProtein generation, Sequence-structure-function, Open weights, Forge API, sequence modeling, structure generation, function design, protein generation

ESM3

Generative protein model that reasons jointly over sequence, structure and function.

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