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Boltz

MIT · #4 most active of 8 in Science & Bio

Compare →

Open-source, AlphaFold3-class biomolecular structure and affinity prediction.

100

Trust score · Verified

3 data points checked · 2026-11-08

Model stack: VerifiedEntry price: VerifiedVersion: VerifiedHow this works →

Current version

Boltz-2

Entry cost

Pricing is not published. API and Enterprise deployments available.

Changes / 30d

5

The short answers · verified November 8, 2026

What is the latest version of Boltz?
The current shipped version of Boltz is Boltz-2, as of November 8, 2026.
How much does Boltz cost?
Boltz has no published flat entry price. Pricing is not published. API and Enterprise deployments available.
What AI model does Boltz use?
Boltz runs primarily on Boltz-2.

Source: MIT — boltz.bio · Reusable under CC BY 4.0 — cite Tomorrow

Capabilities

  • Open weights
  • Affinity prediction
  • Complex structures
  • Local inference
  • Design small molecules
  • Design proteins
  • Predict structures
  • Fine-tuning
  • Python CLI
  • TypeScript SDK
  • TypeScript
  • SOC 2 Type 1
  • small-molecule design
  • protein design
  • structure prediction
  • fine-tuning
  • API
  • biomolecular modeling
  • small-molecule screening
  • hit discovery
  • small molecule design
  • agentic science
  • Molecular Design
  • Protein Design
  • Structure Prediction
  • TypeScript CLI
  • biomolecular design
  • Small-molecule design
  • Protein design
  • Structure prediction
  • design small molecules
  • design proteins
  • predict structures
  • TypeScript API
  • Small Molecule Design
  • On-premise Deployment
  • python cli
  • typescript sdk
  • Small-molecule screening
  • Hit discovery
  • Small molecule design
  • On-premise deployment
  • Biomolecular modeling
  • BoltzMol-1
  • BoltzProt-1
  • Boltz-2
  • BoltzGen
  • python sdk
  • Biomolecular design
  • Boltz API
  • Small-Molecule Design
  • Fine-Tuning
  • API Access
  • Python SDK
  • Molecular design
  • Model fine-tuning

Pricing

Pricing is not published. API and Enterprise deployments available.

Entry price over time

8/7/2026 · $011/8/2026 · $0

Geek mode

Models under the hood

  • Boltz-2

    MIT

    disclosed

  • BoltzGen

    Boltz

    disclosed

  • BoltzMol-1

    Boltz

    disclosed

  • BoltzProt-1

    Boltz

    disclosed

Context window

—

Public API

yes

Multi-model routing

yes

Stack signals

  • python
  • typescript

Shared model stack

Other tracked products running on the same foundation models — a quick read on how much of the catalog moves when one of these models changes.

  • Boltz-2MIT · 1 product
  • BoltzGenBoltz · 1 product
  • BoltzMol-1Boltz · 1 product
  • BoltzProt-1Boltz · 1 product

green disclosed · amber inferred · grey unattributed. Aliases are folded into one model; provider concentration counts only models with an established vendor.

Reported scale

Reference data. Each figure is whatever the source actually said — weekly users, downloads, revenue run-rate — with its own definition and date. These are not comparable between tools and are never used to rank anything.

No public usage figure on record for this product.

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Change history

  • capability

    New capabilities: Molecular design, Model fine-tuning

    54 tracked56 tracked · +Molecular design, Model fine-tuning

    source
  • version

    Boltz moved to Boltz-2

    Boltz APIBoltz-2

    source
  • version

    Boltz moved to Boltz API

    Boltz-2Boltz API

    source
  • capability

    New capabilities: Python SDK

    53 tracked54 tracked · +Python SDK

    source
  • version

    Boltz moved to Boltz-2

    Boltz APIBoltz-2

    source
  • version

    Boltz moved to Boltz API

    Boltz-2Boltz API

    source
  • capability

    New capabilities: Small-Molecule Design, Fine-Tuning, API Access

    50 tracked53 tracked · +Small-Molecule Design, Fine-Tuning, API Access

    source
  • capability

    New capabilities: Boltz API

    49 tracked50 tracked · +Boltz API

    source
  • capability

    New capabilities: Biomolecular design

    48 tracked49 tracked · +Biomolecular design

    source
  • capability

    New capabilities: python sdk

    47 tracked48 tracked · +python sdk

    source
  • capability

    New capabilities: BoltzMol-1, BoltzProt-1, Boltz-2

    43 tracked47 tracked · +BoltzMol-1, BoltzProt-1, Boltz-2, BoltzGen

    source
  • capability

    New capabilities: Biomolecular modeling

    42 tracked43 tracked · +Biomolecular modeling

    source
  • capability

    New capabilities: On-premise deployment

    41 tracked42 tracked · +On-premise deployment

    source
  • version

    Boltz moved to Boltz-2

    Boltz APIBoltz-2

    source
  • version

    Boltz moved to Boltz API

    Boltz-2Boltz API

    source
  • capability

    New capabilities: Small-molecule screening, Hit discovery, Small molecule design

    38 tracked41 tracked · +Small-molecule screening, Hit discovery, Small molecule design

    source
  • version

    Boltz moved to Boltz-2

    Boltz APIBoltz-2

    source
  • version

    Boltz moved to Boltz API

    Boltz-2Boltz API

    source
  • capability

    New capabilities: python cli, typescript sdk

    36 tracked38 tracked · +python cli, typescript sdk

    source
  • version

    Boltz moved to Boltz-2

    Boltz APIBoltz-2

    source
  • capability

    New capabilities: Small Molecule Design, On-premise Deployment

    34 tracked36 tracked · +Small Molecule Design, On-premise Deployment

    source
  • capability

    New capabilities: TypeScript API

    33 tracked34 tracked · +TypeScript API

    source
  • capability

    New capabilities: design small molecules, design proteins, predict structures

    30 tracked33 tracked · +design small molecules, design proteins, predict structures

    source
  • version

    Boltz moved to Boltz API

    Boltz-2Boltz API

    source
  • capability

    New capabilities: Small-molecule design, Protein design, Structure prediction

    27 tracked30 tracked · +Small-molecule design, Protein design, Structure prediction

    source
  • capability

    New capabilities: biomolecular design

    26 tracked27 tracked · +biomolecular design

    source
  • capability

    New capabilities: Molecular Design, Protein Design, Structure Prediction

    22 tracked26 tracked · +Molecular Design, Protein Design, Structure Prediction, TypeScript CLI

    source
  • version

    Boltz moved to Boltz-2

    Boltz APIBoltz-2

    source
  • version

    Boltz moved to Boltz API

    Boltz-2Boltz API

    source
  • capability

    New capabilities: small molecule design, agentic science

    20 tracked22 tracked · +small molecule design, agentic science

    source
  • capability

    New capabilities: biomolecular modeling, small-molecule screening, hit discovery

    17 tracked20 tracked · +biomolecular modeling, small-molecule screening, hit discovery

    source
  • capability

    New capabilities: small-molecule design, protein design, structure prediction

    12 tracked17 tracked · +small-molecule design, protein design, structure prediction, fine-tuning, API

    source
  • capability

    New capabilities: TypeScript, SOC 2 Type 1

    10 tracked12 tracked · +TypeScript, SOC 2 Type 1

    source
  • version

    Boltz moved to Boltz-2

    Boltz APIBoltz-2

    source
  • capability

    New capabilities: Python CLI, TypeScript SDK

    8 tracked10 tracked · +Python CLI, TypeScript SDK

    source
  • version

    Boltz moved to Boltz API

    Boltz-2Boltz API

    source
  • model

    Boltz added BoltzGen, BoltzMol-1, BoltzProt-1 to its model stack

    Boltz-2Boltz-2, BoltzGen, BoltzMol-1, BoltzProt-1

    source
  • capability

    New capabilities: Design small molecules, Design proteins, Predict structures

    4 tracked8 tracked · +Design small molecules, Design proteins, Predict structures, Fine-tuning

    source
Subscribe to Boltz changes

Boltz compared

Straight head-to-head pages against the busiest products in Science & Bio.

Boltz vs ChaiBoltz vs Xaira TherapeuticsBoltz vs Altos LabsBoltz vs Lila SciencesBoltz vs FutureHouseBoltz vs ESM3

How to cite this page

Free to cite and reuse under CC BY 4.0. Permalink: https://tomorrow.aliensquad.ai/tools/boltz

APA
Tomorrow. (2026). Boltz — version, pricing and model stack [Data set entry]. AlienSquad. Retrieved 2026-11-08, from https://tomorrow.aliensquad.ai/tools/boltz
BibTeX
@misc{tomorrow-tools-boltz,
  author       = {{Tomorrow}},
  title        = {Boltz — version, pricing and model stack},
  year         = {2026},
  publisher    = {AlienSquad},
  howpublished = {\url{https://tomorrow.aliensquad.ai/tools/boltz}},
  note         = {Accessed: 2026-11-08}
}